Annals of Surgery, the world’s highest cited surgery journal, is an international source for information on significant contributions to the advancement of surgical science and practice. Surgeons look to Annals first for innovations in practice and technique. Special aspects of the journal include featured articles of major importance to the field with accompanying laser-focused editorials; stimulating Surgical Perspective articles providing opinions on key issues facing all surgeons; and the very best of current surgical science represented by randomized prospective trials, meta-analyses, original articles, and essential review articles.