Gene Expression is an open-access journal dedicated to publishing research at the intersection of science, biology, and medicine. The journal’s mission is to advance human health by providing a platform for disseminating the latest research breakthroughs from biomedical, translational, and basic scientists across both established and emerging disciplines relevant to human translational biomedicine. It was launched in 1991 by Chicago Medical School Press and transferred to Cognizant Communication Corporation in 1994. Since August 2022, Gene Expression has been published by Xia & He Publishing Inc.

Gene Expression publishes peer-reviewed, high-quality original articles, reviews, editorials, commentaries, and opinions on core research topics, including cell biology, molecular biology, genes, and genetics, with a particular focus on the cellular and molecular mechanisms underlying human diseases, specifically in areas such as cardiovascular disease, immunology and vaccines, metabolism, diabetes and obesity, neuroscience, cancer, infectious diseases, aging, biomarkers, gene and cellular therapy, animal models of human diseases, medical integrative omics analysis, epigenetics and regulatory RNAs, and other interdisciplinary approaches.