Nature Chemical Biology is an international monthly journal that provides a high-visibility forum for the publication of top-tier original research and commentary for the chemical biology community. Chemical biology combines the scientific ideas and approaches of chemistry, biology and allied disciplines to understand and manipulate biological systems with molecular precision. The journal publishes papers from the expanding community of chemical biologists, including contributions from chemists who are applying the principles and tools of chemistry to biological questions and from biologists who are interested in understanding and controlling biological processes at the molecular level.