Whenever possible, try to supplement the experiment. If that's not possible, seriously consider providing reasons for defense, but a humble and cautious tone is essential. After all, major revisions also have a certain rejection rate

(0) Thank | 维尔娜菲茨杰拉德

When responding to the comments of the reviewers, all issues must be addressed one by one, without omission; try to meet the experimental needs mentioned in the comments, and explain the reasons why you cannot meet them if you are unable to comply; be sure to cite the literature recommended by the reviewers and discuss them thoroughly; when submitting the revised manuscript, make sure to check the corrections made in the original manuscript.

If you agree with the modifications proposed by the editor when responding to the comments of the journal editor, simply accept the changes. If you disagree, write your reasons directly below the comment and provide feedback to the editor. If there is a disagreement, negotiate further

(0) Thank | 维尔娜菲茨杰拉德

The reviewer requested that I conduct additional experiments, but my samples have already been used up or the experiments have already been completed. Would it be rejected if I simply state that my samples are used up?

(0) Thank | 破戒阳平

What is the difference between responding to reviewers' comments and responding to the editor's comments?

(0) Thank | 陶宜三岁啦