Australasian Physical & Engineering Sciences in Medicine (APESM) is a multidisciplinary forum for information and research on the application of physics and engineering to medicine and human physiology. APESM covers a broad range of topics that include but is not limited to:

- Medical physics in radiotherapy
- Medical physics in diagnostic radiology
- Medical physics in nuclear medicine
- Mathematical modelling applied to medicine and human biology
- Clinical biomedical engineering
- Feature extraction, classification of EEG, ECG, EMG, EOG, and other biomedical signals;
- Medical imaging - contributions to new and improved methods;
- Modelling of physiological systems
- Image processing to extract information from images, e.g. fMRI, CT, etc.;
- Biomechanics, especially with applications to orthopaedics.
- Nanotechnology in medicine

APESM offers original reviews, scientific papers, scientific notes, technical papers, educational notes, book reviews and letters to the editor.

APESM is the journal of the Australasian College of Physical Scientists and Engineers in Medicine, and also the official journal of the College of Biomedical Engineers, Engineers Australia and the Asia-Oceania Federation of Organizations for Medical Physics.